| ncRNA name | hsa-miR-21 |
| ncRNA Category | miRNA |
| Disease name | retinal neovascularization |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal endothelial cells (HRECs) |
| Methods | transfection, qRT-PCR, Western blot, angiogenesis assay |
| Expression pattern | up-regulated |
| Functional description | Our data show that miR-21 mediates STAT3 pro-angiogenic effects in the ischemic retina, thus suggesting its blockade as a potential therapy to prevent/halt RNV. |
| PubMed ID | 29262585 |
| Year | 2017 |
| Title | STAT3-mediated activation of miR-21 is involved in down-regulation of TIMP3 and neovascularization in the ischemic retina. |
| Drug-related ncRNA | NO |
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